Dr. Signe has provided seminars for organizations such as, (in alphabetical order) the Association of Genetic Technologists, Association of Governmental Accountants, Boston University, Commonwealth of Massachusetts, Digital Equipment Corporation, Environmental Protection Agency, Greater Boston Chamber of Commerce, HealthPlex Dental Insurance, Honeywell Bull, Merrill Lynch, Maine Educational Consortium, Physicians For Health Care Access, Suffolk University Law School, University of New Mexico Health Sciences School, and Wellesley College. Interestingly, she did this while suffering from social anxiety disorder which filled her presentations and life with brain-numbing terror.  

As she recovered, she established Effectiveness-Plus LLC to help others "transform social anxiety into social effectiveness" through alleviating performance- and self-presentation anxiety AND sharpening interpersonal communication skills, social intelligence, and personal marketing savvy. She is a certified administrator and interpreter of the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT).

Her latest book, the new and improved 2nd Ed. of Diagonally-Parked in a Parallel Universe: Working Through Social Anxiety (2010), is the social phobic's bible and insider's scoop. Based upon years of research with sufferers and consultation with the pre-eminent clinical researchers in the field, it provides education, treatment, and life-rebuilding strategies.

Notables, such as Dr. Albert Ellis, have praised the book, which has consistently ranked among the ten best-selling anxiety books on Amazon.com.

Author of four other books: How to Win in a Tough Job Market: Successful Strategies for Getting the Job You Want; Create Your Own Career Opportunities; Get the Job You Want: Successful Strategies For Selling Yourself in the Job Market; and Decision Making For Managers, she also contributed to David Riklan's 101 Great Ways to Improve Your Life (Vol. 2) and Steven J. Bennett's Executive Chess: Creative Problem Solving By 45 of America's Top Business Leaders and Thinkers.

Her current e-course is Promote Myself? I'd Rather Eat Worms! 21 Simple Steps to Confidently Tooting Your Own Horn to Achieve Your Goals. Her other home-study program is How to Speak Without Fear Small Talk E-Course.

She has done research at Massachusetts Institute of Technology, Scripps Clinic and Research Foundation, and Fairview State Hospital and presented the findings of her own research on social anxiety, interpersonal effectiveness, and mentoring and networking nationally. 

Because many solo law practitioners, independent professionals, and entrepreneurs are uneasy with attracting clients—due largely to self-promotion reluctance, inadequate marketing strategies, and ineffective marketing conversion—Dr. Signe created her education-based Get Your Ideal Clients Marketing System.

Her coaching and consulting show solo law practitioners and other professionals how to reduce their discomfort, multiply clients and referrals inexpensively and with integrity. Her marketing system uses strategic relationship and communication tactics to create visibility, credibility, rapport, trust, liking, solid relationships to recruit, convert, and retain clients and gain their loyalty. 

A member of International Coach Federation and International Association of Coaches, she coaches internationally. Dr. Signe has done marketing consultation and coaching with attorneys, aesthetic practitioners, dentists, health consultants, clinical nutritionists, psychotherapists, coaches, TV producers, management consultants, CEOs, software developers, and health care organizations, such as Health Action New Mexico. 

To add to her offline marketing expertise, she has taken courses with Internet marketing experts such as Paul Hartunian, Alex Mandossian, Armand Morin, Jim Edwards, Trey Ryder, Dr. Jeff Herring, Drs. Judith Sherven and Jim Sniechowski, Robert Middleton, and Steve Harrison, and is a member of numerous marketing-networking groups, such as Legal Marketing.

An Associate Member of the American Bar Association and their Family Law Section, she has worked with Trey Ryder in his Education-Based Marketing for Lawyers Master Class and with Dr. Clara Mayo who headed Boston University's Jury Project. After having taken several law courses at California Western School of Law, she also worked closely with Dr. Robert Schwartz, Health Law Professor at the University of New Mexico School of Law, on the New Mexico Genetic Information Privacy Act in 1995-1997. 

She has conducted two national surveys to assess (1) what factors lawyers and the public see as contributing to the increasing negative perception by the public of lawyers as a group,  (2) how this negative perception impacts lawyers' attracting and helping clients, and (3) what individual lawyers can do to create positive, education-based, profitable visibility and credibility.  She is also currently surveying lawyers on what strategies they have found to be particularly effective for their individual practices.  

Specializing in coaching and consulting with solo professionals, Dr. Signe has also consulted on enhancing physician-patient communication, created and directed public service health announcement videos for American Cancer Society, promoted the Newton-Wellesley Hospital Oncology Unit, designed promotions and public relations for dentists, provided seminars to genetic counselors and psychologists, and presented to medical students at University of New Mexico Health Sciences School.

She has over 195 published newspaper, magazine, blog posts, and Internet articles and has been quoted in publications including Industry Week, Wall Street Journal, Boston Business Journal, Success, Executive Travel, Time Out New York, Shape, and Cosmopolitan. 

Dr. Signe is also "kitty mom" to rescued "special needs" cats and socializes rescued animals for non-profit CARMA (Companion Animal Rescue and Medical Assistance in Corrales, NM) for adoption to loving homes.